- Title
- Diffusion-weighted imaging of the breast: comparison of B-values 1000 s/mm(2) and 1500 s/mm(2)
- Creator
- Woodhams, Reiko; Inoue, Yusuke; Ramadan, Saadallah; Hata, Hirofumi; Ozaki, Masanori
- Relation
- Magnetic Resonance in Medical Sciences Vol. 12, Issue 3, p. 229-234
- Publisher Link
- http://dx.doi.org/10.2463/mrms.2012-0028
- Publisher
- Japanese Society of Magnetic Resonance in Medicine
- Resource Type
- journal article
- Date
- 2013
- Description
- Purpose: We compared diffusion-weighted imaging (DWI) of the breast using 2 different b-values to determine the optimal b-value for greatest signal contrast between tumors and normal tissue of the breast. Materials and Methods: We performed DWI of the breast at b-values of 1000 s/mm2 and 1500 s/mm2 in 120 patients (121 lesions, 19 benign, 102 malignant) and visually scored image quality with regard to artifact and visibility of tumors. We quantitatively evaluated the signal-to-noise ratio (SNR) of the tumor and contrast-to-noise ratio (CNR) and contrast ratio (CR) between the tumor and normal breast parenchyma. Results: The CR of invasive carcinoma (IC), ductal carcinoma in situ (DCIS), and benign tumors significantly improved with b=1500 s/mm2 compared with b=1000 s/mm2. The SNR and CNR were significantly lower with b=1500 s/mm2 than b=1000 s/mm2 despite the increasing number of excitations at b=1500 s/mm2. At b=1500 s/mm2, the difference in SNR, CNR, and CR between IC and DCIS and benign tumors was statistically significant. Conclusion: DWI may depict breast tumors more clearly with b=1500 s/mm2 than b=1000 s/mm2.
- Subject
- b-value; breast; diffusion-weighted imaging
- Identifier
- http://hdl.handle.net/1959.13/1067243
- Identifier
- uon:18367
- Identifier
- ISSN:1347-3182
- Language
- eng
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